| A2020 |
Denosumab (anti-RANK ligand)
|
Denosumab (anti-RANK ligand) (AMG-162) 是是一種全人源單克隆抗體,可選擇性抑制靈長類動(dòng)物 RANKL。Denosumab 可抑制 human RANKL (143–317) 刺激源自鼠 RAW 264.7 細(xì)胞的破骨細(xì)胞形成的能力,IC50 值為 1.64 nM。 |
-
STAR Protoc, 2025, 6(2):103719
-
Cell Rep Med, 2024, 5(10):101757
-
Allergy Asthma Immunol Res, 2024, 16(4):399-421
|
|
| S9276 |
Alisol B
|
Alisol B, a triterpene from Alismatis rhizoma, induces Bax up-regulation and nuclear translocation, the activation of initiator caspase-8 and caspase-9, and executor caspase-3, suggesting the involvement of both extrinsic and intrinsic apoptosis pathways. |
|
|
| S9050 |
Boldine
|
Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects. |
|
|