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      • Bcl-2
      • Bcl-B
      • Bcl-w
      • Bcl-xL
      • Mcl-1
      • Bax
      • Bfl-1
      • Bad
      • Bcl-xL

      Bfl-1 抑制劑

      目錄號 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S8061 Sabutoclax Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively. Pan Bfl-1, IC50: 0.62 μM
      S2448 Gambogic Acid Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively. Pan Bfl-1, IC50: 1.06 μM
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