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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S7424	PD 151746	PD 151746 is a selective, cell-permeable calpain inhibitor with K_i of 0.26 μM for μ-Calpain, about 20-fold selectivity over m-calpain.	Selective	μ-Calpain, IC50: 260 nM; m-calpain, IC50: 5.33 μM
S7394	MDL-28170	MDL-28170 (Calpain Inhibitor III) is a potent and selective calpain inhibitor of calpain that penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration. MDL-28170 is also an inhibitor of γ-secretase.	Selective
S7396	Calpeptin	Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Calpeptin attenuates apoptosis and intracellular inflammatory changes in muscle cells.	Pan	Calpain I (porcine erythrocytes), ID50: 52 nM; Calpain II (porcine kidney), ID50: 34 nM; Calpain I (human platelets), ID50: 40 nM

Calpain 選擇性抑制劑