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      • Estrogen receptor
      • Progesterone receptor
      • ERR

      ERR 選擇性激活劑 | 激動(dòng)劑 | 調(diào)節(jié)劑

      目錄號(hào) 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S3449 GSK5182 GSK5182, 4-hydroxytamoxifen analog, is a specific inverse agonist of estrogen-related receptor γ (ERRγ) that inhibits pro-inflammatory cytokine-induced catabolic factors. Selective
      S0143 WAY-200070 WAY-200070 is a selective estrogen receptor β (ERRβ) agonist with an IC50 of 2.3 nM. Selective ERRβ, IC50: 2.3 nM
      S0407 XCT790 XCT-790 (Compound 12) is a potent and selective inverse agonist for estrogen-related receptor α (ERRα) with IC50 of 0.37 μM. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ. XCT-790 (Compound 12) significantly inhibits in vivo tumor growth and angiogenesis, and induces apoptosis. Selective ERRα, IC50: 0.37 μM
      S2314 Kaempferol (NSC 407289) Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase. Selective
      S0358 GSK4716 GSK4716 is a selective agonist of Estrogen-Related Orphan Nuclear Receptors ERR and ERRγ with an IC50 of 2 μM in the ERRγ FRET assay. Selective
      S5364 DY131 DY131 is a potent and selective ERRβ/γ activator. It has no effect on the structurally related receptors ERRalpha or the estrogen receptors alpha and beta (ERalpha/beta). Selective
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