GLI 選擇性抑制劑
| 目錄號 |
產(chǎn)品名 |
產(chǎn)品描述 |
Selective / Pan |
IC50 / Ki |
| S6565 |
JK184 |
JK184 inhibits Gli in the Hedgehog (Hh) pathway with IC50 of 30 nM in mammalian cells. |
Selective |
|
| S8075 |
GANT61 |
GANT61 (NSC 136476) is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM in GLI1 expressing HEK293T cell, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation. GANT61 induces apoptosis and activates protective autophagy in LX-2 cells. |
Selective |
GLI1, IC50: 5 μM |
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