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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S6492	Doravirine (MK-1439)	Doravirine (MK-1439) is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. It is highly specific with minimum off-target activities.	Selective	WT HIV-1 RT, IC50: 12 nM; K103N HIV-1 RT, IC50: 9.7 nM; Y181C HIV-1 RT, IC50: 9.7 nM
S2914	Dapivirine (TMC120)	Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.	Selective	HIV reverse transcriptase, IC50: 24 nM
S6452	Delavirdine mesylate	Delavirdine Mesylate(U 90152 mesylate) is a mesylate salt form of delavirdine, which is a synthetic, non-nucleoside reverse transcriptase inhibitor.	Selective	HIV1 RT, IC50: 0.26 μM
S3165	Abacavir sulfate	Abacavir (1592U89) is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.	Selective
S1400	Tenofovir (GS 1278) Disoproxil Fumarate	Tenofovir Disoproxil Fumarate (Tenofovir DF,GS-1278 Disoproxil Fumarate) belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.	Selective
S1719	Zalcitabine	Zalcitabine (NSC 606170, Ro 24-2027/000) is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).	Selective

HIV-RT 選擇性抑制劑