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      • PDE1
      • PDE2
      • PDE3
      • PDE4
      • PDE5
      • PDE6
      • PDE10A
      • PDE9
      • PDE4B

      PDE6 抑制劑

      目錄號 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S5957 Vardenafil hydrochloride Vardenafil (BAY38-9456, Levitra, Staxyn) hydrochloride is a selective, orally active, potent inhibitor of phosphodiesterase (PDE) with IC50 of 0.7 nM, 11 nM and 180 nM for PDE5, PDE6 and PDE1, respectively. Pan PDE6, IC50: 11 nM
      S1431 Sildenafil Citrate Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well-tolerated and highly effective treatment for erectile dysfunction. Pan PDE6, IC50: 33 nM
      S6433 Udenafil Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25 nM and a comparable selectivity profile as sildenafil for the other PDEs. Pan PDE6, IC50: 53.3 nM
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