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      • PDE1
      • PDE2
      • PDE3
      • PDE4
      • PDE5
      • PDE6
      • PDE10A
      • PDE9
      • PDE4B

      PDE9 選擇性抑制劑

      目錄號(hào) 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S0039 BI-409306 BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with mean IC50 of 65 nM and 168 nM, respectively. Treatment with BI 409306 increases brain cGMP levels, promotes long-term potentiation, and improves episodic and working memory performance in rodents. Selective human PDE9A, IC50: 65 nM; rat PDE9A, IC50: 168 nM
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