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      TAS2R 選擇性激動(dòng)劑
      
        
      
            
            
      
                目錄號(hào)
                產(chǎn)品名
                產(chǎn)品描述
                Selective / Pan
                IC50 / Ki
            
      
                  
            
            
                
      
                    S1273
                    Amarogentin
                    
      Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. Amarogentin induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. Amarog
      		
                    Selective
                    
                
      
            
                  
        
      
        
    
      

      
    







      


      
    
    
    
    
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