Aldose Reductase

Aldose Reductase產(chǎn)品

所有產(chǎn)品(9)
Aldose Reductase抑制劑 (9)
新Aldose Reductase產(chǎn)品

目錄號	產(chǎn)品名	產(chǎn)品描述	文獻引用
S2404	Isoliquiritigenin	Isoliquiritigenin 是Glycyrrhiza glabra根系分泌的一種類黃酮，能抑制醛糖還原酶，IC50為320 nM。具有抗腫瘤活性。	J Nutr Biochem, 2024, 136:109808 Biomedicines, 2022, 10(3)638 Cancer Res, 2021, 81(16):4257-4274
S2035	Epalrestat	Epalrestat是一種醛糖還原酶 aldose reductase抑制劑，IC50為72 nM。	Cell Rep Med, 2023, 4(6):101056 Cell Rep Med, 2023, 4(6):101056 Free Radic Biol Med, 2021, 163:220-233
S5803	Alrestatin	Alrestatin是aldose reductase (醛糖還原酶)抑制劑。醛糖還原酶參與了糖尿病并發(fā)癥，包括糖尿病神經(jīng)病變的發(fā)病機理。	iScience, 2022, 25(4):104153
S9196	Calceolarioside B	Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.
S3245	Nodakenetin	Nodakenetin (NANI) 是從Angelica decursiva中分離出的植物性香豆素，可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改變 Bax 和 Bcl-2 的蛋白質(zhì)表達，并促進線粒體凋亡。Nodakenetin 具有抗腫瘤活性。
E2456	Soyasaponin Bb	Soyasaponin Bb是一種從Phaseolus vulgaris中分離出來的大豆皂苷，是一種醛糖還原酶 (aldose reductase, AKR1B1)差異抑制劑 (ARDI)。
S1074	Poliumoside	Poliumoside對于晚期糖基化終產(chǎn)物的形成有顯著抑制作用，IC50值為19.69 μM。在大鼠晶狀體醛糖還原酶測定試驗中，發(fā)現(xiàn) Poliumoside對rat lens aldose reductase(RLAR)表現(xiàn)出抑制作用，IC50值為8.47 μM。
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S9198	Obtusifolin	Obtusifolin is anthraquinone found in the seeds of Cassia obtusifolia, has inhibitory effects on platelet aggregation and aldose reductase.
S2404	Isoliquiritigenin	Isoliquiritigenin 是Glycyrrhiza glabra根系分泌的一種類黃酮，能抑制醛糖還原酶，IC50為320 nM。具有抗腫瘤活性。	J Nutr Biochem, 2024, 136:109808 Biomedicines, 2022, 10(3)638 Cancer Res, 2021, 81(16):4257-4274
S2035	Epalrestat	Epalrestat是一種醛糖還原酶 aldose reductase抑制劑，IC50為72 nM。	Cell Rep Med, 2023, 4(6):101056 Cell Rep Med, 2023, 4(6):101056 Free Radic Biol Med, 2021, 163:220-233
S5803	Alrestatin	Alrestatin是aldose reductase (醛糖還原酶)抑制劑。醛糖還原酶參與了糖尿病并發(fā)癥，包括糖尿病神經(jīng)病變的發(fā)病機理。	iScience, 2022, 25(4):104153
S9196	Calceolarioside B	Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.
S3245	Nodakenetin	Nodakenetin (NANI) 是從Angelica decursiva中分離出的植物性香豆素，可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改變 Bax 和 Bcl-2 的蛋白質(zhì)表達，并促進線粒體凋亡。Nodakenetin 具有抗腫瘤活性。
E2456	Soyasaponin Bb	Soyasaponin Bb是一種從Phaseolus vulgaris中分離出來的大豆皂苷，是一種醛糖還原酶 (aldose reductase, AKR1B1)差異抑制劑 (ARDI)。
S1074	Poliumoside	Poliumoside對于晚期糖基化終產(chǎn)物的形成有顯著抑制作用，IC50值為19.69 μM。在大鼠晶狀體醛糖還原酶測定試驗中，發(fā)現(xiàn) Poliumoside對rat lens aldose reductase(RLAR)表現(xiàn)出抑制作用，IC50值為8.47 μM。
S5446	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative.
S9198	Obtusifolin	Obtusifolin is anthraquinone found in the seeds of Cassia obtusifolia, has inhibitory effects on platelet aggregation and aldose reductase.