IFN

IFN產(chǎn)品

所有產(chǎn)品(51)
IFN抑制劑 (12)
IFN抗體 (15)
IFN激活劑 (6)
IFN激動劑 (2)
新IFN產(chǎn)品

目錄號	產(chǎn)品名	產(chǎn)品描述	文獻(xiàn)引用
S1537	Vadimezan (DMXAA)	Vadimezan (DMXAA)是一種vascular disrupting agents (VDA)，也是一種DT-diaphorase的競爭性抑制劑，無細(xì)胞試驗(yàn)中Ki為20 μM ，IC50為62.5 μM。DMXAA (Vadimezan) 也是一種STING 激動劑，具有潛在的抗腫瘤活性。DMXAA (Vadimezan) 在體外可有效誘導(dǎo) IFN-β 和 TNF-α 的表達(dá)，但對 TNF-α 影響相對較低。DMXAA (Vadimezan)具有抗病毒活性。Phase 3。	Cell Chem Biol, 2025, 32(2):280-290.e14 Commun Biol, 2025, 8(1):1470 Front Pharmacol, 2025, 16:1528459
S6494	CCCP	CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone)是一種氧化磷酸化抑制劑，是線粒體質(zhì)子載體解偶聯(lián)劑，可增加線粒體膜對質(zhì)子的通透性，從而破壞線粒體膜電位。	Mol Cell, 2025, 85(7):1467-1476.e6 Life Sci, 2025, 380:123965 iScience, 2025, 28(8):112972
S8133	Resiquimod (R-848)	Resiquimod (R-848, S28463)是一種免疫反應(yīng)調(diào)節(jié)劑，用作有效的TLR 7/TLR 8激動劑并可誘導(dǎo)如 TNF-α、IL-6 和 IFN-α 等細(xì)胞因子的上調(diào)。Resiquimod 可減少 hepatitis C virus (HCV)感染。Phase 2。	Nature, 2025, 644(8078):1058-1068 J Virol, 2025, e0128025. Int J Nanomedicine, 2024, 19:3589-3605
S7259	FLLL32	FLLL32 是一種有效的 JAK2/STAT3 抑制劑，IC50 <5 μM。FLLL32 在乳腺癌細(xì)胞中通過 IFNα 和 IL-6 來抑制STAT3磷酸化的誘導(dǎo)。	Stem Cell Reports, 2025, 20(10):102673 Cancer Commun -Lond), 2023, 43(10):1117-1142 Microbiol Res, 2023, 276:127480
S3544	VBIT-4	VBIT-4 是一種 voltage-dependent anion channel (VDAC) oligomerization 的抑制劑，可降低在系統(tǒng)性紅斑狼瘡小鼠模型中 mitochondrial DNA (mtDNA) 的釋放、type I interferon (IFN) 的信號傳導(dǎo)、中性粒細(xì)胞胞外陷阱和疾病的嚴(yán)重性。	Cell Rep, 2025, 44(5):115605 Cell Rep, 2025, 44(6):115834 Aging Cell, 2025, 24(9):e70135
S3023	Bufexamac	Bufexamac(Bufexamic acid)是一種COX抑制劑，靶點(diǎn)是IFN-α， EC50 為8.9 μM。	Biomedicines, 2024, 12(6)1203 Int J Mol Sci, 2021, 22(9)4559 Reprod Sci, 2021, 10.1007/s43032-021-00533-2
S5588	Creatine	Creatine (Methylguanidoacetic acid) 是一種天然存在于脊椎動物中的含氮有機(jī)酸。Creatine 可以通過抑制 IFN-γ receptors 與 JAK2 的相互作用來抑制 JAK-STAT1 信號傳遞，以ATP非依賴性的方式促進(jìn)三磷酸腺苷（ATP）的循環(huán)，從而抑制下游促炎基因表達(dá)。	Aging (Albany NY), 2022, 14(16):6796-6808 Cancer Cell, 2021, S1535-6108(21)00445-1 Histochem Cell Biol, 2021, 156(3):227-237
S3924	Ginsenoside Rb1	Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.	J Biol Chem, 2024, 300(8):107542 J Ethnopharmacol, 2021, S0378-8741(21)00169-0 J Biol Chem, 2021, S0021-9258(21)00790-0
S2259	Aloe-emodin	Aloe-emodin (NSC 38628, Rhabarberone) 是一種干擾素誘導(dǎo)劑，作用于JEV，IC50為1 μg/mL，作用于EV71，IC50為0.33 μg/mL。	PLoS One, 2019, 14(4):e0215664 J Tradit Complement Med, 2015, 5(2):96-9
A2121	Anti-mouse IFNAR-1-InVivo	Anti-mouse IFNAR-1-InVivo 單克隆抗體（克隆號：MAR1-5A3）可與 mouse IFNAR-1 (IFN alpha/beta receptor subunit 1)發(fā)生反應(yīng)。Anti-mouse IFNAR-1-InVivo 已被證明可在體外和體內(nèi)抑制 I 型 IFN 受體信號傳導(dǎo)。	Cell Commun Signal, 2025, 23(1):99 EMBO Rep, 2025, 10.1038/s44319-025-00541-2 Cell Rep, 2023, 42(1):112002
S8879	Deucravacitinib (BMS-986165)	Deucravacitinib (BMS-986165)是一種強(qiáng)效的、選擇性的 Tyk2 的變構(gòu)抑制劑，其與 Tyk2 假激酶結(jié)構(gòu)域結(jié)合的Ki值為0.02 nM。它對一組265種激酶和假激酶的實(shí)驗(yàn)中具有高度的選擇性。	Res Sq, 2025, rs.3.rs-6079043 Nat Commun, 2024, 15(1):1718 Nat Commun, 2024, 15(1):1337
S0289	KIN1148	KIN1148 是一種 interferon regulatory factor 3 (IRF3) 的激動劑，可誘導(dǎo)劑量依賴性IRF3核易位和IRF3反應(yīng)性啟動子的特異性激活。KIN1148 是一種流感疫苗佐劑，可增強(qiáng)流感疫苗的功效。	J Allergy Clin Immunol, 2022, S0091-6749(22)01423-3
S8954	G10 (STING agonist-1)	G10 (STING agonist-1)是一種新型人類特異性 STING 激動劑，可在人成纖維細(xì)胞中觸發(fā) IFN regulatory factor 3 (IRF3)/ type I interferon (IFN) 相關(guān)轉(zhuǎn)錄。STING agonist-1 (G10) 可有效抑制 Chikungunya virus (CHIKV) 的生長，IC90值為8.01 μM 和 Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV)的復(fù)制，IC90為24.57 μM。	Int J Biol Sci, 2023, 19(11):3428-3440
S0437	SAR-20347	SAR-20347 是一種有效的 TYK2、JAK1、JAK2 和 JAK3 的抑制劑，對應(yīng)的IC50值為0.6 nM、23 nM、26 nM和41 nM。SAR-20347可抑制TYK2和JAK1介導(dǎo)的 IL-12 和 IFN-α 信號傳導(dǎo)。	Cancer Discov, 2023, 13(2):410-431 Cancer Discov, 2023, 13(2):410-431
F0521	IRF3 Antibody [N18A4]	IRF3,IRF-3
F1399	MAVS Antibody [P1P22]
F0180	T-BET Antibody [B2D24]	T-bet,T-bet / Tbx21,T-bet/TBX21
F0543	IRF-8 Antibody [B21B7]
F2436	IRF5 Antibody [P8P6]	IRF5,IRF-5
F2494	IRF2 Antibody [G24C1]		Mater Today Bio, 2025, 35:102498
S1833	Butoconazole nitrate	Butoconazole nitrate (RS-35887)是一種抗真菌劑，抑制PHA刺激下人外周血淋巴細(xì)胞中細(xì)胞因子（如IL-2, TNFα, IFN 和 GM-CSF）的分泌，IC50分別為7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。
E2982	IFN alpha-IFNAR-IN-1 hydrochloride	IFN alpha-IFNAR-IN-1 hydrochloride是一種非肽類、低分子量抑制劑，可抑制 IFN-α 和 IFNAR 之間的相互作用。 IFN α-IFNAR-IN-1 saltchide 可抑制小鼠骨髓來源的 Flt3-L 分化的 pDC 培養(yǎng)物 (BM-pDC) 中修飾的安卡拉牛痘病毒 (MVA) 誘導(dǎo)的 IFN-α 反應(yīng)，IC50 值為 2-8 μM。
A2152	Anti-mouse IFNγ (XMG1.2)-InVivo	Anti-mouse IFNγ (XMG1.2)-InVivo與小鼠 IFNγ（干擾素γ）發(fā)生反應(yīng)，IFNγ 是一種 20 kDa 可溶性多效性細(xì)胞因子，也是 II 型干擾素的唯一成員。	Front Immunol, 2025, 16:1527934 Antib Ther, 2024, 7(3):266-280
C0066^New	Recombinant Human IFN-γ Protein, BSA (HEK293)	Recombinant Human IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Gln166.
C0067^New	Recombinant Canine IFN-γ Protein, BSA (HEK293)	Recombinant Canine IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Lys166.
C0068^New	Recombinant Human IFN-β Protein, BSA (HEK293)	Recombinant Human IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Met22-Asn187.
C0069^New	Recombinant Mouse IFN-β Protein, BSA (HEK293)	Recombinant Mouse IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile22-Asn182.
A2867	Fontolizumab (Anti-IFNg)	Fontolizumab (anti-IFNg)是一種針對干擾素-γ（IFN-g）的人源化單克隆抗體，具有免疫調(diào)節(jié)活性。分子量：144.8。
S3827	Royal jelly acid	Royal jelly acid (10-Hydroxy-trans-2-decenoic acid, 10H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.
A2460	Anifrolumab (Anti-IFNAR1)	Anifrolumab (Anti-IFNAR1)是一種人單克隆抗體。它是一種 I 型干擾素 (IFN) 受體拮抗劑，可阻斷 I 型干擾素的活性。 Anifrolumab 可用于系統(tǒng)性紅斑狼瘡 (SLE) 的研究。分子量：145.5KD。	Clin Transl Med, 2025, 15(5):e70323 Clin Transl Med, 2025, 15(5):e70323
A2461	Sifalimumab (Anti-IFNa1)	Sifalimumab (Anti-IFNa1) 是一種抗 IFNα 單克隆抗體。Sifalimumab通過與多種干擾素-α (IFNα) 亞型結(jié)合來抑制異常免疫活性。分子量：145.5KD。
A2664	Rontalizumab (Anti-IFNa1)	Rontalizumab (Anti-IFNa1)是一種針對 IFN-α 的人源化 IgG1 單克隆抗體。可用于系統(tǒng)性紅斑狼瘡的研究。分子量：150 KD。
S5020	Tilorone dihydrochloride	Tilorone dihydrochloride是一種廣譜的、具有口服活性的抗病毒試劑，可激活干擾素的生成。它具有抗腫瘤和抗炎活性。
S7904	2',3'-cGAMP Sodium Salt	2',3'-cGAMP Sodium Salt (2'-3'-cyclic GMP-AMP Sodium)是響應(yīng)哺乳動物細(xì)胞質(zhì)中的DNA產(chǎn)生的，并能以高親和力結(jié)合 STING，且有效地誘導(dǎo) interferon-β (IFNβ)。2',3'-cGAMP 結(jié)合 STING 的Kd值為3.79 nM。	J Nanobiotechnology, 2025, 23(1):724 Cancer Sci, 2025, 10.1111/cas.70162 J Biol Chem, 2025, 301(10):110653
S7905	3',3'-cGAMP	3',3'-cGAMP (3',3'-cyclic GMP-AMP, Cyclic GMP-AMP, cGAMP)可激活內(nèi)質(zhì)網(wǎng)(ER)內(nèi)源性受體 stimulator of interferon genes (STING) ，從而誘導(dǎo)抗病毒狀態(tài)和I型IFN的分泌。
A2938	Anti-IFNg (AMG 811)	Anti-IFNg (AMG 811) 是一種人單克隆抗體（IgG1 同種型），選擇性靶向人 IFNgamma 7。它具有治療系統(tǒng)性紅斑狼瘡 (SLE) 的潛力。分子量：144.36KD。
E5781	2',3'-cGAMP	2',3'-cGAMP（2'-3'-cyclic GMP-AMP）是哺乳動物細(xì)胞響應(yīng)細(xì)胞質(zhì) DNA 而產(chǎn)生的內(nèi)源性環(huán)狀 GMP-AMP。它與 STING 結(jié)合，親和力 Kd 高達(dá) 3.79 nM，是干擾素-β (IFNβ) 的強(qiáng)效誘導(dǎo)劑。	Commun Biol, 2025, 8(1):1470
A2105	Anti-mouse IFNγ-InVivo	R4-6A2單克隆抗體與小鼠IFNγ(interferon gamma)反應(yīng)。IFNγ是一種20 kDa的可溶性多效性細(xì)胞因子，是II型干擾素的唯一成員。R4-6A2抗體可中和天然和重組IFNγ。	J Immunother Cancer, 2025, 13(7)e011948 Cell Commun Signal, 2025, 23(1):99 Nat Commun, 2024, 15(1):4913
E0448	RO8191	RO8191 (CDM-3008, RO4948191) 是一種咪唑萘啶化合物，是一種具有口服活性的強(qiáng)效干擾素 (IFN) 受體激動劑。 RO8191 直接與 IFNα/β 受體 2 (IFNAR2) 結(jié)合，激活 IFN 刺激基因 (ISG) 的表達(dá)和 JAK/STAT 信號傳導(dǎo)的磷酸化。
C0155^New	Recombinant Mouse IL-28B/IFN-lambda 3 protein, BSA (HEK293)	Recombinant Mouse IL-28B/IFN-lambda 3 protein is expressed from HEK293 with His tag at the C-Terminus.
C0156^New	Recombinant Mouse IL-28B/IFN-lambda 3 protein, CF (HEK293)	Recombinant Mouse IL-28B/IFN-lambda 3 protein is expressed from HEK293 with His tag at the C-Terminus.
C0157^New	Recombinant Mouse IL-28A/IFN-lambda 2 protein, BSA (HEK293)	Recombinant Mouse IL-28A/IFN-lambda 2 protein is expressed from HEK293 with His tag at the C-Terminus.
C0158^New	Recombinant Mouse IL-28A/IFN-lambda 2 protein, CF (HEK293)	Recombinant Mouse IL-28A/IFN-lambda 2 protein is expressed from HEK293 with His tag at the C-Terminus.
C0189^New	Recombinant Human IL-29 / IFN-lambda 1 Protein, BSA (HEK293)	Recombinant Human IL-29 / IFN-lambda 1 Protein is expressed from HEK293 with His tag at the C-terminus.
C0141^New	Recombinant Human IFN-γ Protein, CF (HEK293)	Recombinant Human IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Gln166.
C0190^New	Recombinant Human IL-29 / IFN-lambda 1 Protein, CF (HEK293)	Recombinant Human IL-29 / IFN-lambda 1 Protein is expressed from HEK293 with His tag at the C-terminus.
C0142^New	Recombinant Canine IFN-γ Protein, CF (HEK293)	Recombinant Canine IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Lys166.
C0143^New	Recombinant Human IFN-β Protein, CF (HEK293)	Recombinant Human IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Met22-Asn187.
C0144^New	Recombinant Mouse IFN-β Protein, CF (HEK293)	Recombinant Mouse IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile22-Asn182.
S6727	AX-024 HCl	AX-024 HCl 可抑制CD3ε PRS與SH3.1(Nck)的相互作用。AX-024 HCl 可抑制 IL-6、TNF-α、IFN-γ、IL-10 和 IL-17A。	Cell Rep Med, 2025, S2666-3791(25)00231-9
A2041	Emapalumab (anti-IFNγ)	Emapalumab (anti-IFNγ)是一種針對IFNγ的單克隆抗體，是第一個全球批準(zhǔn)用于治療難治性原發(fā)性噬血性血細(xì)胞淋巴組織細(xì)胞增多癥(HLH)的兒童和成人患者的治療方法。	Cell Rep Med, 2025, 6(11):102434 Cell Death Discov, 2025, 11(1):9 Blood Adv, 2024, bloodadvances.2023012522
S6494	CCCP	CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone)是一種氧化磷酸化抑制劑，是線粒體質(zhì)子載體解偶聯(lián)劑，可增加線粒體膜對質(zhì)子的通透性，從而破壞線粒體膜電位。	Mol Cell, 2025, 85(7):1467-1476.e6 Life Sci, 2025, 380:123965 iScience, 2025, 28(8):112972
S7259	FLLL32	FLLL32 是一種有效的 JAK2/STAT3 抑制劑，IC50 <5 μM。FLLL32 在乳腺癌細(xì)胞中通過 IFNα 和 IL-6 來抑制STAT3磷酸化的誘導(dǎo)。	Stem Cell Reports, 2025, 20(10):102673 Cancer Commun -Lond), 2023, 43(10):1117-1142 Microbiol Res, 2023, 276:127480
S3544	VBIT-4	VBIT-4 是一種 voltage-dependent anion channel (VDAC) oligomerization 的抑制劑，可降低在系統(tǒng)性紅斑狼瘡小鼠模型中 mitochondrial DNA (mtDNA) 的釋放、type I interferon (IFN) 的信號傳導(dǎo)、中性粒細(xì)胞胞外陷阱和疾病的嚴(yán)重性。	Cell Rep, 2025, 44(5):115605 Cell Rep, 2025, 44(6):115834 Aging Cell, 2025, 24(9):e70135
S3023	Bufexamac	Bufexamac(Bufexamic acid)是一種COX抑制劑，靶點(diǎn)是IFN-α， EC50 為8.9 μM。	Biomedicines, 2024, 12(6)1203 Int J Mol Sci, 2021, 22(9)4559 Reprod Sci, 2021, 10.1007/s43032-021-00533-2
S5588	Creatine	Creatine (Methylguanidoacetic acid) 是一種天然存在于脊椎動物中的含氮有機(jī)酸。Creatine 可以通過抑制 IFN-γ receptors 與 JAK2 的相互作用來抑制 JAK-STAT1 信號傳遞，以ATP非依賴性的方式促進(jìn)三磷酸腺苷（ATP）的循環(huán)，從而抑制下游促炎基因表達(dá)。	Aging (Albany NY), 2022, 14(16):6796-6808 Cancer Cell, 2021, S1535-6108(21)00445-1 Histochem Cell Biol, 2021, 156(3):227-237
S3924	Ginsenoside Rb1	Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.	J Biol Chem, 2024, 300(8):107542 J Ethnopharmacol, 2021, S0378-8741(21)00169-0 J Biol Chem, 2021, S0021-9258(21)00790-0
S8879	Deucravacitinib (BMS-986165)	Deucravacitinib (BMS-986165)是一種強(qiáng)效的、選擇性的 Tyk2 的變構(gòu)抑制劑，其與 Tyk2 假激酶結(jié)構(gòu)域結(jié)合的Ki值為0.02 nM。它對一組265種激酶和假激酶的實(shí)驗(yàn)中具有高度的選擇性。	Res Sq, 2025, rs.3.rs-6079043 Nat Commun, 2024, 15(1):1718 Nat Commun, 2024, 15(1):1337
S0437	SAR-20347	SAR-20347 是一種有效的 TYK2、JAK1、JAK2 和 JAK3 的抑制劑，對應(yīng)的IC50值為0.6 nM、23 nM、26 nM和41 nM。SAR-20347可抑制TYK2和JAK1介導(dǎo)的 IL-12 和 IFN-α 信號傳導(dǎo)。	Cancer Discov, 2023, 13(2):410-431 Cancer Discov, 2023, 13(2):410-431
S1833	Butoconazole nitrate	Butoconazole nitrate (RS-35887)是一種抗真菌劑，抑制PHA刺激下人外周血淋巴細(xì)胞中細(xì)胞因子（如IL-2, TNFα, IFN 和 GM-CSF）的分泌，IC50分別為7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。
E2982	IFN alpha-IFNAR-IN-1 hydrochloride	IFN alpha-IFNAR-IN-1 hydrochloride是一種非肽類、低分子量抑制劑，可抑制 IFN-α 和 IFNAR 之間的相互作用。 IFN α-IFNAR-IN-1 saltchide 可抑制小鼠骨髓來源的 Flt3-L 分化的 pDC 培養(yǎng)物 (BM-pDC) 中修飾的安卡拉牛痘病毒 (MVA) 誘導(dǎo)的 IFN-α 反應(yīng)，IC50 值為 2-8 μM。
S3827	Royal jelly acid	Royal jelly acid (10-Hydroxy-trans-2-decenoic acid, 10H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.
S6727	AX-024 HCl	AX-024 HCl 可抑制CD3ε PRS與SH3.1(Nck)的相互作用。AX-024 HCl 可抑制 IL-6、TNF-α、IFN-γ、IL-10 和 IL-17A。	Cell Rep Med, 2025, S2666-3791(25)00231-9
A2121	Anti-mouse IFNAR-1-InVivo	Anti-mouse IFNAR-1-InVivo 單克隆抗體（克隆號：MAR1-5A3）可與 mouse IFNAR-1 (IFN alpha/beta receptor subunit 1)發(fā)生反應(yīng)。Anti-mouse IFNAR-1-InVivo 已被證明可在體外和體內(nèi)抑制 I 型 IFN 受體信號傳導(dǎo)。	Cell Commun Signal, 2025, 23(1):99 EMBO Rep, 2025, 10.1038/s44319-025-00541-2 Cell Rep, 2023, 42(1):112002
F0521	IRF3 Antibody [N18A4]	IRF3,IRF-3
F1399	MAVS Antibody [P1P22]
F0180	T-BET Antibody [B2D24]	T-bet,T-bet / Tbx21,T-bet/TBX21
F0543	IRF-8 Antibody [B21B7]
F2436	IRF5 Antibody [P8P6]	IRF5,IRF-5
F2494	IRF2 Antibody [G24C1]		Mater Today Bio, 2025, 35:102498
A2152	Anti-mouse IFNγ (XMG1.2)-InVivo	Anti-mouse IFNγ (XMG1.2)-InVivo與小鼠 IFNγ（干擾素γ）發(fā)生反應(yīng)，IFNγ 是一種 20 kDa 可溶性多效性細(xì)胞因子，也是 II 型干擾素的唯一成員。	Front Immunol, 2025, 16:1527934 Antib Ther, 2024, 7(3):266-280
A2867	Fontolizumab (Anti-IFNg)	Fontolizumab (anti-IFNg)是一種針對干擾素-γ（IFN-g）的人源化單克隆抗體，具有免疫調(diào)節(jié)活性。分子量：144.8。
A2460	Anifrolumab (Anti-IFNAR1)	Anifrolumab (Anti-IFNAR1)是一種人單克隆抗體。它是一種 I 型干擾素 (IFN) 受體拮抗劑，可阻斷 I 型干擾素的活性。 Anifrolumab 可用于系統(tǒng)性紅斑狼瘡 (SLE) 的研究。分子量：145.5KD。	Clin Transl Med, 2025, 15(5):e70323 Clin Transl Med, 2025, 15(5):e70323
A2461	Sifalimumab (Anti-IFNa1)	Sifalimumab (Anti-IFNa1) 是一種抗 IFNα 單克隆抗體。Sifalimumab通過與多種干擾素-α (IFNα) 亞型結(jié)合來抑制異常免疫活性。分子量：145.5KD。
A2664	Rontalizumab (Anti-IFNa1)	Rontalizumab (Anti-IFNa1)是一種針對 IFN-α 的人源化 IgG1 單克隆抗體。可用于系統(tǒng)性紅斑狼瘡的研究。分子量：150 KD。
A2938	Anti-IFNg (AMG 811)	Anti-IFNg (AMG 811) 是一種人單克隆抗體（IgG1 同種型），選擇性靶向人 IFNgamma 7。它具有治療系統(tǒng)性紅斑狼瘡 (SLE) 的潛力。分子量：144.36KD。
A2105	Anti-mouse IFNγ-InVivo	R4-6A2單克隆抗體與小鼠IFNγ(interferon gamma)反應(yīng)。IFNγ是一種20 kDa的可溶性多效性細(xì)胞因子，是II型干擾素的唯一成員。R4-6A2抗體可中和天然和重組IFNγ。	J Immunother Cancer, 2025, 13(7)e011948 Cell Commun Signal, 2025, 23(1):99 Nat Commun, 2024, 15(1):4913
A2041	Emapalumab (anti-IFNγ)	Emapalumab (anti-IFNγ)是一種針對IFNγ的單克隆抗體，是第一個全球批準(zhǔn)用于治療難治性原發(fā)性噬血性血細(xì)胞淋巴組織細(xì)胞增多癥(HLH)的兒童和成人患者的治療方法。	Cell Rep Med, 2025, 6(11):102434 Cell Death Discov, 2025, 11(1):9 Blood Adv, 2024, bloodadvances.2023012522
S1537	Vadimezan (DMXAA)	Vadimezan (DMXAA)是一種vascular disrupting agents (VDA)，也是一種DT-diaphorase的競爭性抑制劑，無細(xì)胞試驗(yàn)中Ki為20 μM ，IC50為62.5 μM。DMXAA (Vadimezan) 也是一種STING 激動劑，具有潛在的抗腫瘤活性。DMXAA (Vadimezan) 在體外可有效誘導(dǎo) IFN-β 和 TNF-α 的表達(dá)，但對 TNF-α 影響相對較低。DMXAA (Vadimezan)具有抗病毒活性。Phase 3。	Cell Chem Biol, 2025, 32(2):280-290.e14 Commun Biol, 2025, 8(1):1470 Front Pharmacol, 2025, 16:1528459
S8133	Resiquimod (R-848)	Resiquimod (R-848, S28463)是一種免疫反應(yīng)調(diào)節(jié)劑，用作有效的TLR 7/TLR 8激動劑并可誘導(dǎo)如 TNF-α、IL-6 和 IFN-α 等細(xì)胞因子的上調(diào)。Resiquimod 可減少 hepatitis C virus (HCV)感染。Phase 2。	Nature, 2025, 644(8078):1058-1068 J Virol, 2025, e0128025. Int J Nanomedicine, 2024, 19:3589-3605
S2259	Aloe-emodin	Aloe-emodin (NSC 38628, Rhabarberone) 是一種干擾素誘導(dǎo)劑，作用于JEV，IC50為1 μg/mL，作用于EV71，IC50為0.33 μg/mL。	PLoS One, 2019, 14(4):e0215664 J Tradit Complement Med, 2015, 5(2):96-9
S8954	G10 (STING agonist-1)	G10 (STING agonist-1)是一種新型人類特異性 STING 激動劑，可在人成纖維細(xì)胞中觸發(fā) IFN regulatory factor 3 (IRF3)/ type I interferon (IFN) 相關(guān)轉(zhuǎn)錄。STING agonist-1 (G10) 可有效抑制 Chikungunya virus (CHIKV) 的生長，IC90值為8.01 μM 和 Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV)的復(fù)制，IC90為24.57 μM。	Int J Biol Sci, 2023, 19(11):3428-3440
S5020	Tilorone dihydrochloride	Tilorone dihydrochloride是一種廣譜的、具有口服活性的抗病毒試劑，可激活干擾素的生成。它具有抗腫瘤和抗炎活性。
S7905	3',3'-cGAMP	3',3'-cGAMP (3',3'-cyclic GMP-AMP, Cyclic GMP-AMP, cGAMP)可激活內(nèi)質(zhì)網(wǎng)(ER)內(nèi)源性受體 stimulator of interferon genes (STING) ，從而誘導(dǎo)抗病毒狀態(tài)和I型IFN的分泌。
S0289	KIN1148	KIN1148 是一種 interferon regulatory factor 3 (IRF3) 的激動劑，可誘導(dǎo)劑量依賴性IRF3核易位和IRF3反應(yīng)性啟動子的特異性激活。KIN1148 是一種流感疫苗佐劑，可增強(qiáng)流感疫苗的功效。	J Allergy Clin Immunol, 2022, S0091-6749(22)01423-3
E0448	RO8191	RO8191 (CDM-3008, RO4948191) 是一種咪唑萘啶化合物，是一種具有口服活性的強(qiáng)效干擾素 (IFN) 受體激動劑。 RO8191 直接與 IFNα/β 受體 2 (IFNAR2) 結(jié)合，激活 IFN 刺激基因 (ISG) 的表達(dá)和 JAK/STAT 信號傳導(dǎo)的磷酸化。
C0066^New	Recombinant Human IFN-γ Protein, BSA (HEK293)	Recombinant Human IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Gln166.
C0067^New	Recombinant Canine IFN-γ Protein, BSA (HEK293)	Recombinant Canine IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Lys166.
C0068^New	Recombinant Human IFN-β Protein, BSA (HEK293)	Recombinant Human IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Met22-Asn187.
C0069^New	Recombinant Mouse IFN-β Protein, BSA (HEK293)	Recombinant Mouse IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile22-Asn182.
C0155^New	Recombinant Mouse IL-28B/IFN-lambda 3 protein, BSA (HEK293)	Recombinant Mouse IL-28B/IFN-lambda 3 protein is expressed from HEK293 with His tag at the C-Terminus.
C0156^New	Recombinant Mouse IL-28B/IFN-lambda 3 protein, CF (HEK293)	Recombinant Mouse IL-28B/IFN-lambda 3 protein is expressed from HEK293 with His tag at the C-Terminus.
C0157^New	Recombinant Mouse IL-28A/IFN-lambda 2 protein, BSA (HEK293)	Recombinant Mouse IL-28A/IFN-lambda 2 protein is expressed from HEK293 with His tag at the C-Terminus.
C0158^New	Recombinant Mouse IL-28A/IFN-lambda 2 protein, CF (HEK293)	Recombinant Mouse IL-28A/IFN-lambda 2 protein is expressed from HEK293 with His tag at the C-Terminus.
C0189^New	Recombinant Human IL-29 / IFN-lambda 1 Protein, BSA (HEK293)	Recombinant Human IL-29 / IFN-lambda 1 Protein is expressed from HEK293 with His tag at the C-terminus.
C0141^New	Recombinant Human IFN-γ Protein, CF (HEK293)	Recombinant Human IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Gln166.
C0190^New	Recombinant Human IL-29 / IFN-lambda 1 Protein, CF (HEK293)	Recombinant Human IL-29 / IFN-lambda 1 Protein is expressed from HEK293 with His tag at the C-terminus.
C0142^New	Recombinant Canine IFN-γ Protein, CF (HEK293)	Recombinant Canine IFN-γ Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln24-Lys166.
C0143^New	Recombinant Human IFN-β Protein, CF (HEK293)	Recombinant Human IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Met22-Asn187.
C0144^New	Recombinant Mouse IFN-β Protein, CF (HEK293)	Recombinant Mouse IFN-β Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile22-Asn182.