Mineralocorticoid Receptor

Mineralocorticoid Receptor產(chǎn)品

所有產(chǎn)品(5)
Mineralocorticoid Receptor抑制劑 (1)
Mineralocorticoid Receptor拮抗劑 (4)
新Mineralocorticoid Receptor產(chǎn)品

目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	文獻(xiàn)引用
S1707	Eplerenone	Eplerenone是一類mineralocorticoid receptor 拮抗劑，阻斷了醛固酮的作用，用于控制高血壓。	J Immunother Cancer, 2024, 12(11)e009805 Acta Pharm Sin B, 2023, 13(2):662-677 Oncol Rep, 2021, 46(3)202
E1239	Apararenone	Apararenone (MT-3995) 是一種選擇性的長(zhǎng)效非甾體鹽皮質(zhì)激素受體(mineralocorticoid receptors, MR)拮抗劑。
S5273	Canrenone	Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
S9702	Finerenone (BAY 94-8862)	Finerenone (FIN, BAY 94-8862) 是一種高度選擇性的、口服活性的 mineralocorticoid receptor (MR) 的非甾體拮抗劑，IC50值為18 nM。Finerenone 具有研究諸如2型糖尿病和慢性腎臟病等心腎疾病的潛力。
E0704	Esaxerenone (CS-3150)	Esaxerenone (CS-3150)是一種選擇性非甾體鹽皮質(zhì)受體(nonsteroidal mineralocorticoid receptor, MR)拮抗劑，與鹽皮質(zhì)受體結(jié)合，抑制(3)H-醛固酮與鹽皮質(zhì)受體結(jié)合，IC50為9.4 nM。Esaxerenone (CS-3150)增加蛋白尿恢復(fù)到正常水平的可能性，并減少蛋白尿進(jìn)展到更高水平。
E0704	Esaxerenone (CS-3150)	Esaxerenone (CS-3150)是一種選擇性非甾體鹽皮質(zhì)受體(nonsteroidal mineralocorticoid receptor, MR)拮抗劑，與鹽皮質(zhì)受體結(jié)合，抑制(3)H-醛固酮與鹽皮質(zhì)受體結(jié)合，IC50為9.4 nM。Esaxerenone (CS-3150)增加蛋白尿恢復(fù)到正常水平的可能性，并減少蛋白尿進(jìn)展到更高水平。
S1707	Eplerenone	Eplerenone是一類mineralocorticoid receptor 拮抗劑，阻斷了醛固酮的作用，用于控制高血壓。	J Immunother Cancer, 2024, 12(11)e009805 Acta Pharm Sin B, 2023, 13(2):662-677 Oncol Rep, 2021, 46(3)202
E1239	Apararenone	Apararenone (MT-3995) 是一種選擇性的長(zhǎng)效非甾體鹽皮質(zhì)激素受體(mineralocorticoid receptors, MR)拮抗劑。
S5273	Canrenone	Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.
S9702	Finerenone (BAY 94-8862)	Finerenone (FIN, BAY 94-8862) 是一種高度選擇性的、口服活性的 mineralocorticoid receptor (MR) 的非甾體拮抗劑，IC50值為18 nM。Finerenone 具有研究諸如2型糖尿病和慢性腎臟病等心腎疾病的潛力。