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      • DBH
      • KMO
      • TPH

      DBH 選擇性抑制劑

      目錄號(hào) 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S2695 Nepicastat (SYN-117) HCl Nepicastat (SYN-117) HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Phase 2. Selective Bovine dopamine-beta-hydroxylase, IC50: 8.5 nM; Human dopamine-beta-hydroxylase, IC50: 9 nM
      S4926 (R)-Nepicastat HCl (R)-Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Selective Bovine dopamine-beta-hydroxylase, IC50: 25.1 nM; Human dopamine-beta-hydroxylase, IC50: 18.3 nM
      S3273 Hypericin Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Selective
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