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H-ras
N-ras
K-ras
Ral

H-ras 選擇性抑制劑

目錄號	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S8303	Kobe0065	Kobe0065 is an H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.	Selective
S2797	Lonafarnib (SCH66336)	Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.	Pan	H-ras, IC50: 1.9 nM

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