MAP4K7 選擇性抑制劑
| 目錄號 |
產(chǎn)品名 |
產(chǎn)品描述 |
Selective / Pan |
IC50 / Ki |
| S8392 |
NCB-0846 |
NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase, MAP4K7) with an IC50 value of 21 nM. |
Selective |
TNIK, IC50: 21 nM |
| S0268 |
DMX-5084 |
DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively. |
Pan |
TNIK/MAP4K7, pIC50: 7.96 |
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