MCT1 選擇性抑制劑
| 目錄號(hào) |
產(chǎn)品名 |
產(chǎn)品描述 |
Selective / Pan |
IC50 / Ki |
| S6732 |
7ACC2 |
7ACC2 is a potent inhibitor of mitochondrial pyruvate transport 1 (MCT1) with an IC50 value of 10 nM for lactate uptake in SiHa human cervix carcinoma cells. |
Selective |
|
| S7339 |
AZD3965 |
AZD3965 is a potent, selective and orally available monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM, 6-fold selective over MCT2. Phase 1. |
Selective |
|
| S7919 |
AR-C155858 |
AR-C155858 is a selective?monocarboxylate transporter?MCT1?and?MCT2 inhibitor with?Ki value of 2.3 nM and 10 nM, respectively. |
Pan |
MCT1, Ki: 2.3 nM |
| S9907 |
Syrosingopine |
Syrosingopine is a dual MCT1 and MCT4 inhibitor with IC50 values of 2500nM and 40 nM in HAP1 cells, respectively.
|
Pan |
MCT1, IC50: 2500 nM |
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