| S2642 |
1-Naphthyl PP1(1-NA-PP1) |
1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively. |
Selective |
PKD1, IC50: 154.6 nM; PKD2, IC50: 133.4 nM; PKD3, IC50: 109.4 nM |
| S7188 |
CID755673 |
CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.
|
Selective |
PKD1, IC50: 180 nM; PKD2, IC50: 280 nM; PKD3, IC50: 227 nM |
