| S4701 |
2-Deoxy-D-glucose (2-DG)
|
2-DG (2-Deoxy-D-glucose), 一種葡萄糖類似物,是具有抗病毒活性的糖酵解抑制劑。2-Deoxy-D-glucose 可誘導(dǎo)凋亡并抑制 Herpes Simplex Virus type-1 (HSV-1) receptor 的表達(dá)。 |
-
Signal Transduct Target Ther, 2025, 10(1):341
-
Nat Commun, 2025, 16(1):212
-
Cancer Commun (Lond), 2025, 10.1002/cac2.70036
|
|
| S8047 |
Dynasore
|
Dynasore 是一種細(xì)胞滲透性的,可逆的,非競(jìng)爭(zhēng)性dynamin抑制劑,抑制dynamin 1/2的GTPase活性,無(wú)細(xì)胞試驗(yàn)中IC50為15 μM,也抑制線粒體dynamin Drp1,對(duì)其他小GTP酶沒(méi)有作用效果。Dynasore 可抑制 mTORC1 活性并誘導(dǎo)自噬。Dynasore 抑制多種病毒的入侵,包括HSV。 |
-
J Nanobiotechnology, 2025, 23(1):173
-
Cell Death Dis, 2025, 16(1):681
-
Blood Adv, 2025, bloodadvances.2024015296
|
|
| S7546 |
Pritelivir (BAY 57-1293)
|
Pritelivir (BAY 57-1293, AIC316)是一種強(qiáng)效的helicase primase抑制劑, 其對(duì)單純性皰疹病毒(HSV)HSV-1 和 HSV-2具有抗病毒作用,IC50為20 nM。
|
-
PLoS Pathog, 2021, 17(11):e1010117
-
J Virol, 2021, JVI0166621
|
|
| S8428 |
FSL-1
|
FSL-1是一種細(xì)菌來(lái)源的toll樣受體2/6 (toll-like receptor 2/6, TLR2/6)激動(dòng)劑,可增強(qiáng)對(duì)實(shí)驗(yàn)性HSV-2感染的抵抗力。 |
|
|
| S9070 |
(2S)-(-)-isoxanthohumol
|
(2S)-(-)-isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). |
|
|
| S4701 |
2-Deoxy-D-glucose (2-DG)
|
2-DG (2-Deoxy-D-glucose), 一種葡萄糖類似物,是具有抗病毒活性的糖酵解抑制劑。2-Deoxy-D-glucose 可誘導(dǎo)凋亡并抑制 Herpes Simplex Virus type-1 (HSV-1) receptor 的表達(dá)。 |
- Signal Transduct Target Ther, 2025, 10(1):341
- Nat Commun, 2025, 16(1):212
- Cancer Commun (Lond), 2025, 10.1002/cac2.70036
|
|
| S8047 |
Dynasore
|
Dynasore 是一種細(xì)胞滲透性的,可逆的,非競(jìng)爭(zhēng)性dynamin抑制劑,抑制dynamin 1/2的GTPase活性,無(wú)細(xì)胞試驗(yàn)中IC50為15 μM,也抑制線粒體dynamin Drp1,對(duì)其他小GTP酶沒(méi)有作用效果。Dynasore 可抑制 mTORC1 活性并誘導(dǎo)自噬。Dynasore 抑制多種病毒的入侵,包括HSV。 |
- J Nanobiotechnology, 2025, 23(1):173
- Cell Death Dis, 2025, 16(1):681
- Blood Adv, 2025, bloodadvances.2024015296
|
|
| S7546 |
Pritelivir (BAY 57-1293)
|
Pritelivir (BAY 57-1293, AIC316)是一種強(qiáng)效的helicase primase抑制劑, 其對(duì)單純性皰疹病毒(HSV)HSV-1 和 HSV-2具有抗病毒作用,IC50為20 nM。
|
- PLoS Pathog, 2021, 17(11):e1010117
- J Virol, 2021, JVI0166621
|
|
| S8428 |
FSL-1
|
FSL-1是一種細(xì)菌來(lái)源的toll樣受體2/6 (toll-like receptor 2/6, TLR2/6)激動(dòng)劑,可增強(qiáng)對(duì)實(shí)驗(yàn)性HSV-2感染的抵抗力。 |
|
|
| S9070 |
(2S)-(-)-isoxanthohumol
|
(2S)-(-)-isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). |
|
|