5-HT1
5-HT2
5-HT3
5-HT4
5-HT6
5-HT7
5-HT5

5-HT3 選擇性激動(dòng)劑 | 拮抗劑

目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S4694	Alosetron Hydrochloride	Alosetron Hydrochloride (GR 68755C, GR 68755X, Lotronex) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.	Selective
S5052	Granisetron	Granisetron (Sancuso, Kevatril, Granisetronum, Sustol) is a serotonin receptor (5HT-3 selective) antagonist that is used as an antiemetic and antinauseant for cancer chemotherapy.	Selective
S2865	VUF 10166	VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with K_i of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.	Selective	5-HT3A, Ki: 0.04 nM; 5-HT3AB, Ki: 22 nM
S3723	Ramosetron Hydrochloride	Ramosetron Hydrochloride (YM-060) is the hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity.	Selective	5-HT3 receptor, Ki: 0.091 nM
S5740	Palonosetron	Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).	Selective	5-HT3 receptor, Ki: 0.17 nM
S2106	Azasetron HCl	Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.	Selective	5-HT3, IC50: 0.33 nM
S5538	Tropisetron	Tropisetron (ICS 205-930) is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.	Selective	5-HT3 receptor, Ki: 5.3 nM
S2644	Lerisetron	Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.	Selective	5-HT3 receptor, IC50: 0.81 μM
S4748	Ondansetron Hydrochloride Dihydrate	Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.	Selective	5-HT3 receptor, IC50: 810 nM
S2578	1-Phenylbiguanide	1-Phenylbiguanide (Phenylbiguanide, PBG, N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3) receptor agonist with EC50 of 3.0 μM.	Selective	5-HT3 receptor, EC50: 3.0 μM
S1898	Tropisetron HCl	Tropisetron HCl (ICS 205-930) is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.	Selective
S1345	Granisetron HCl	Granisetron is a serotonin 5-HT3 receptor antagonist,used to treat chemotherapy-induced nausea and vomiting.	Selective
S3050	Palonosetron HCl	Palonosetron HCl (RS 25259, RS 25259 197) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.	Selective
S1996	Ondansetron	Ondansetron (GR 38032F, GR-C507/75,SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.	Selective
S1390	Ondansetron HCl	Ondansetron HCl is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.	Selective