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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S6971	Ervogastat	Ervogastat (PF-06865571, DGAT2i) is a potent diacylglycerol acyltransferase 2 (DGAT2) inhibitor that reduces steatosis and hepatic triglyceride levels in non-alcoholic steatohepatitis (NASH).	Pan
S9921	PF-06424439	PF-06424439 is a first orally bioavailable small-molecule inhibitor of DGAT2 with an IC50 of 14 nM.	Pan	DGAT2, IC50: 14 nM
S7192	PF-04620110	PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.	Pan	DGAT1, IC50: 19 nM
s7889	Xanthohumol	Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 μM. Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses. Xanthohumol induces growth inhibition and apoptosis in cancer cells. Phase 1.	Pan	DGAT1, IC50: 40 μM; DGAT2, IC50: 40 μM

DGAT 抑制劑