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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S8601	CP2	CP2 is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively.	Selective	KDM4A, IC50: 42 nM; KDM4C, IC50: 29 nM
S7296	ML324	ML324 is a selective inhibitor of jumonji histone demethylase (JMJD2) with IC50 of 920 nM.	Selective	JMJD2, IC50: 920 nM
S0201	Z-JIB-04 (NSC 693627)	Z-JIB-04 (NSC 693627, JIB-04 Z-isomer) is an isomer of JIB-04. JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230 nM, 340 nM, 855 nM, 445 nM, 435 nM, 1100 nM and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.	Pan	JMJD2E, IC50: 340 nM; JMJD2A, IC50: 445 nM; JMJD2B, IC50: 435 nM; JMJD2C, IC50: 1100 nM; JMJD2D, IC50: 290 nM
S7281	JIB-04	JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D in cell-free assays, respectively. JIB?04 also induces cell apoptosis.	Pan	JMJD2E, IC50: 340 nM; JMJD2A, IC50: 445 nM; JMJD2B, IC50: 435 nM; JMJD2D, IC50: 290 nM
S7234	IOX1	IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 is an inhibitor of ALKBH5.	Pan	KDM4C, IC50: 0.6 μM

JMJD2 選擇性抑制劑