| S4699 |
Etretinate |
Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. |
Selective |
|
| S1569 |
Tazarotene |
Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. |
Selective |
|
| S4627 |
TTNPB |
TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. |
Selective |
RARα, IC50: 5.1 nM; RARβ , IC50: 4.5 nM; RARγ, IC50: 9.3 nM |
| S4260 |
Tamibarotene |
Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ. |
Selective |
|
| S1276 |
Adapalene |
Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne. |
Pan |
|
| S1653 |
Retinoic acid (Tretinoin) |
Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. |
Pan |
|
