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      • δ-opioid receptor
      • κ-opioid receptor
      • μ-opioid receptor
      • ORL1

      κ-opioid receptor 選擇性抑制劑 | 激動(dòng)劑 | 拮抗劑

      目錄號(hào) 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S0009 Asimadoline hydrochloride Asimadoline hydrochloride (EMD-61753 hydrochloride) is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Selective guinea pig κ-opioid, IC50: 5.6 nM; recombined human κ-opioid, IC50: 1.2 nM
      S2322 (+)-Matrine Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist. Selective
      S5935 Alvimopan Alvimopan (LY 246736, ADL 8-2698) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors. Pan κ-opioid receptor, Ki: 40 nM
      S5701 Alvimopan dihydrate (LY246736 dihydrate) Alvimopan (LY-246736) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors. Pan κ-opioid receptor, Ki: 40 nM
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