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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S6618	JNJ-42153605	JNJ-42153605 is a potent and selective mGlu2 receptor positive allosteric modulator with an EC50 of 17 nM.	Selective	mGlu2 receptor, EC50: 17 nM
S6001	pomaglumetad (LY404039)	LY404039 is a potent agonist of recombinant human mGlu2/mGlu3 receptors with K_i of 149 nM/92 nM, shows >100-fold selectivity over ionotropic glutamate receptors, glutamate transporters, and other receptors. Phase 3.	Pan	Recombinant human mGlu2, Ki: 149 nM; Rat neurons expressing native mGlu2/3, Ki: 88 nM

mGluR2 選擇性激動(dòng)劑 | 調(diào)節(jié)劑