PTEN

PTEN產(chǎn)品

• 所有產(chǎn)品(8)
• PTEN抑制劑 (3)
• PTEN抗體 (3)
• PTEN激活劑 (2)
• 新PTEN產(chǎn)品

目錄號	產(chǎn)品名	產(chǎn)品描述	文獻(xiàn)引用	實(shí)驗(yàn)數(shù)據(jù)
S7310	SF1670	SF1670是一種高度有效且專一的PTEN的抑制劑，其IC50 為 2 μM。	Oncol Rep, 2025, 54(4)125 Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9 J Biol Chem, 2024, S0021-9258(24)01808-8
S8651	bpV (HOpic)	bpV (HOpic) (Bisperoxovanadium (HOpic))是一種有效的PTEN抑制劑，IC50為14 nM。它對PTP-β和PTP-1B的IC50值分別約是對PTEN的IC50的350倍和1800倍。	Brain Behav Immun, 2025, 130:106111 Cell Death Dis, 2025, 16(1):226 Stem Cell Res Ther, 2025, 16(1):455
S8174	VO-Ohpic trihydrate	VO-Ohpic是一種有效的PTEN (phosphatase and tensin homolog)抑制劑，IC50為35 nM。	Cell Commun Signal, 2025, 23(1):431 Nature, 2024, 631(8019):170-178 Aging (Albany NY), 2023, 15(6):2275-2292
S9190	Oroxin B	Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.	Environ Pollut, 2023, 323:121306 Theranostics, 2022, 12(2):910-928 J Cancer, 2021, 12(7):2140-2150
F0499	Phospho-PTEN (Ser380/Thr382/383) Antibody [K19C17]	Phospho-PTEN (Ser380),Phospho-PTEN (Ser380/Thr382/383),PTEN (phospho S380)
F2618	Phospho-PTEN (Thr366) Antibody [A11K14]
S0918	Ginkgolic acid C17:1	Ginkgolic acid C17:1 (GAC 17:1) 通過廢除上游的 JAK2 和 Src 來抑制 STAT3 的組成性激活。Ginkgolic acid C17:1 可以誘導(dǎo) PTEN 和 SHP-1 的大量表達(dá)。Ginkgolic acid C17:1 誘導(dǎo)腫瘤細(xì)胞凋亡。
F3548New	PTEN Antibody [J22G2]
S7310	SF1670	SF1670是一種高度有效且專一的PTEN的抑制劑，其IC50 為 2 μM。	Oncol Rep, 2025, 54(4)125 Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9 J Biol Chem, 2024, S0021-9258(24)01808-8
S8651	bpV (HOpic)	bpV (HOpic) (Bisperoxovanadium (HOpic))是一種有效的PTEN抑制劑，IC50為14 nM。它對PTP-β和PTP-1B的IC50值分別約是對PTEN的IC50的350倍和1800倍。	Brain Behav Immun, 2025, 130:106111 Cell Death Dis, 2025, 16(1):226 Stem Cell Res Ther, 2025, 16(1):455
S8174	VO-Ohpic trihydrate	VO-Ohpic是一種有效的PTEN (phosphatase and tensin homolog)抑制劑，IC50為35 nM。	Cell Commun Signal, 2025, 23(1):431 Nature, 2024, 631(8019):170-178 Aging (Albany NY), 2023, 15(6):2275-2292
F0499	Phospho-PTEN (Ser380/Thr382/383) Antibody [K19C17]	Phospho-PTEN (Ser380),Phospho-PTEN (Ser380/Thr382/383),PTEN (phospho S380)
F2618	Phospho-PTEN (Thr366) Antibody [A11K14]
F3548New	PTEN Antibody [J22G2]
S9190	Oroxin B	Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.	Environ Pollut, 2023, 323:121306 Theranostics, 2022, 12(2):910-928 J Cancer, 2021, 12(7):2140-2150
S0918	Ginkgolic acid C17:1	Ginkgolic acid C17:1 (GAC 17:1) 通過廢除上游的 JAK2 和 Src 來抑制 STAT3 的組成性激活。Ginkgolic acid C17:1 可以誘導(dǎo) PTEN 和 SHP-1 的大量表達(dá)。Ginkgolic acid C17:1 誘導(dǎo)腫瘤細(xì)胞凋亡。
F3548New	PTEN Antibody [J22G2]