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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S5795	Rasagiline	Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.	Selective	MAO-B, IC50: 4.43 nM
S2102	Rasagiline Mesylate	Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.	Selective	MAO-B, IC50: 4.43 nM
S6422	Lazabemide	Lazabemide (Ro 19-6327) is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM.	Selective	MAO-B, Ki: 7.9 nM
S5357	Safinamide	Safinamide (EMD-1195686, PNU-15774E) is an orally active, selective, reversible monoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.	Selective	MAO-B, Ki: 16.7 nM
S1472	Safinamide Mesylate	Safinamide Mesylate (PNU-151774E, FCE28073) is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.	Selective	MAO-B, IC50: 98 nM
S6602	TB5	TB5 is a potent and selective MAO-B inhibitor with Ki values of 110 and 1,450 nM for MAO-B and MAO-A, respectively.	Selective	MAO-B, Ki: 110 nM
S3690	Pargyline hydrochloride	Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectivey.	Selective	MAO-B, Ki: 0.5 μM
S4246	Tranylcypromine (2-PCPA) HCl	Tranylcypromine HCl (2-PCPA, SKF-385, Parnate) is a monoamine oxidase inhibitor, which inhibits CYP2A6 with K_i of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.	Pan	MAO-B, IC50: 7 μM
S4717	Isatin	Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.	Pan	MAO-B, IC50: 14 μM
S2339	Paeonol	Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.	Pan	MAO-B, IC50: 42.5 μM

MAO-B 選擇性抑制劑