| S2833 |
UVI 3003 |
UVI 3003 is a highly selective antagonist of?retinoid X receptor (RXR) with?IC50 of 0.24 μM against human RXR. |
Selective |
RXR, IC50: 0.24 μM |
| S2098 |
Bexarotene |
Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. |
Selective |
|
| S1276 |
Adapalene |
Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne. |
Pan |
|
| S1653 |
Retinoic acid (Tretinoin) |
Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. |
Pan |
|
