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目錄號(hào)	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S5935	Alvimopan	Alvimopan (LY 246736, ADL 8-2698) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.	Pan	δ-opioid receptor, IC50: 4.4 nM; δ-opioid receptor, Ki: 4.4 nM
S5701	Alvimopan dihydrate (LY246736 dihydrate)	Alvimopan (LY-246736) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.	Pan	δ-opioid receptor, Ki: 4.4 nM
S2480	Loperamide HCl	Loperamide HCl (ADL 2-1294,R-18553 hydrochloride) is a selective μ-opioid receptor agonist opioid with K_i of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.	Pan	δ-opioid receptor, Ki: 48 nM

δ-opioid receptor 抑制劑 | 激動(dòng)劑 | 拮抗劑