- 抑制劑
- 化合物庫
- 抗體
- 生物試劑
- qPCR
- 2x SYBR Green qPCR Master Mix
- 2x SYBR Green qPCR Master Mix(Low ROX)
- 2x SYBR Green qPCR Master Mix(High ROX)
- 蛋白實(shí)驗(yàn)
- Protein A/G免疫沉淀磁珠
- Anti-DYKDDDDK Tag免疫磁珠
- Anti-DYKDDDDK Tag親和凝膠
- Anti-Myc免疫磁珠
- Anti-HA免疫磁珠
- 磁力架
- Poly DYKDDDDK Tag多肽
- 細(xì)胞核與細(xì)胞漿蛋白抽提試劑盒
- 免疫磁珠
- 蛋白酶抑制劑Cocktail
- 蛋白酶抑制劑Cocktail(DMSO儲液)
- 磷酸酶抑制劑Cocktail
- 細(xì)胞實(shí)驗(yàn)
- Cell Counting Kit-8 (CCK-8)
- 新產(chǎn)品
- 聯(lián)系我們
- NMDA receptor
- AMPA receptor
- mGluR2
- mGluR3
- mGluR4
- mGluR5
mGluR4 選擇性激動劑
| 目錄號 | 產(chǎn)品名 | 產(chǎn)品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S8035 | VU 0364439 | VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM. | Selective | mGluR4, EC50: 19.8 nM |
| S2892 | VU 0361737 | VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS. | Selective | mGluR4 (Human), EC50: 240 nM; mGluR4 (Rat ), EC50: 110 nM |
| S2862 | VU 0364770 | VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes. | Selective | mGlu4, EC50: 1.1 μM |
