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      • S1PR1
      • S1PR4
      • S1PR5
      • S1PR2

      S1PR1 選擇性激動(dòng)劑 | 調(diào)節(jié)劑

      目錄號 產(chǎn)品名 產(chǎn)品描述 Selective / Pan IC50 / Ki
      S7952 Ozanimod Ozanimod is a selective oral S1P Receptor 1 modulator. Phase 3. Selective S1P1R, EC50: 0.41 nM
      S8241 Ponesimod Ponesimod (ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM. Selective S1P1 receptor, EC50: 5.7 nM
      S7179 Siponimod (BAF312) BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3. Pan S1P1 receptor, EC50: 0.39 nM
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