蛋白降解

分子膠 & PROTAC

分子膠

Avadomide

Iberdomide

BI-3802

Pomalidomide

Mezigdomide

Indisulam

E7820

CC-99282

Thalidomide

Tasisulam

(R)-CR8 trihydrochloride

Sodium 2-(1H-indol-3-yl)acetate

Lenalidomide

Cyclosporin A

dCeMM1

PROTAC

Gefitinib-based PROTAC 3

MS4078

dBET57

MT-802

dBET1

ARV-825

ARV-771

dBET6

A1874

GMB-475

DT2216

THAL-SNS-032

UNC6852

PROTAC SGK3 degrader-1

GSK215

ADC

Trastuzumab deruxtecan

Sacituzumab govitecan

Trastuzumab Emtansine（T-DM1）

Patritumab deruxtecan

Vorsetuzumab mafodotin

Anetumab-MMAE

Clivatuzumab-MMAE

Indusatumab vedotin

Lifastuzumab vedotin

Anetumab ravtansine

Polatuzumab vedotin-piiq

Zilovertamab vedotin

Farletuzumab-MMAE

Iladatuzumab vedotin

Pinatuzumab vedotin

Sirtratumab vedotin

Codrituzumab-MMAE

Cetuximab-MMAE

Tusamitamab ravtansine

Serclutamab talirine

Cantuzumab ravtansine

Ozuriftamab vedotin

Sofituzumab vedotin

Laprituximab emtansine

Enapotamab vedotin

Praluzatamab ravtansine

Depatuxizumab mafodotin

多泛素化修飾

泛素連接酶E3

Lenalidomide

Pomalidomide

Thalidomide

Nutlin-3

Serdemetan

泛素結(jié)合酶 E2

NSC697923

NAcM-OPT

泛素活化酶 E1

Pevonedistat

TAK-243

PYR-41

ML792

COH000

去泛素化酶

BAY 11-7082

PR-619

P5091

Degrasyn

Spautin-1

P22077

類泛素化修飾

2-D08

Subasumstat

Ginkgolic Acid

momordin-Ic

NSC 632839

含纈酪肽蛋白

NMS-873

CB-5083

DBeQ

MNS

CB-5339

NPD8733

蛋白酶體降解

26S蛋白酶體

MG132

(±)-Shikonin

20S蛋白酶體

Isoginkgetin

Bortezomib

Ixazomib Citrate

Ixazomib Citrate (MLN9708) Analogue

Marizomib

Delanzomib

ONX-0914

Oprozomib

Celastrol

Epoxomicin

Carfilzomib

VR23

線粒體自噬調(diào)控 ^[1]

NAD

Nicotinamide Riboside Chloride

β-nicotinamide mononucleotide

Nicotinic Acid

Luteolin

SIRT1/3

Resveratrol

Honokiol

Selisistat

SRT1720 HCl

3-TYP

SRT2104

SRT2183

USP30

MF-094

p53

Pifithrin-α (PFTα) Hhydrobromide

(-)-Parthenolide

Metformin Hydrochloride

Doxorubicin

Harpagoside

Nrf2

Sulforaphane

Tomatidine Hydrochloride

PINK1

Gemcitabine

1400W 2HCl

MCL-1

UMI-77

VU661013

AZD5991

S63845

MIK665

A-1210477

溶酶體途徑

蛋白轉(zhuǎn)運(yùn)

Brefeldin A

Sodium Monensin

Exo1

溶酶體降解

Bafilomycin A1

EN6

KM91104

Hydroxychloroquine (HCQ) Sulfate

DC661

內(nèi)吞調(diào)控

Dansylcadaverine 

Pitstop 2

Methyl-β-cyclodextrin

Chlorpromazine

相關(guān)化合物庫(kù)

Protease Inhibitor Library

Protein-protein Interaction Inhibitor Library

Ubiquitination Compound Library

Autophagy Compound Library