原料藥(僅用于科研)

目錄號	產(chǎn)品名	產(chǎn)品描述
S1250	Enzalutamide (MDV3100)	Enzalutamide是一種androgen-receptor (AR)拮抗劑，在 LNCaP細胞中IC50為36 nM。研究證明 Enzalutamide 可促進自噬。
S1696	Hydrocortisone	Hydrocortisone是一種由腎上腺產(chǎn)生的類固醇激素或糖皮質激素。
S7297	Osimertinib (AZD9291)	Osimertinib (AZD9291, Mereletinib)是口服不可逆的，突變選擇性EGFR抑制劑，在 LoVo細胞中對Exon 19 缺失的 EGFR，L858R/T790M EGFR，和 WT EGFR的IC50分別為12.92，11.44 和 493.8 nM。Phase 3。
S9521	Pentostatin	Pentostatin(CI-825,Deoxycoformycin)是有效的腺甙脫氨酶抑制劑，在治療多種惡性淋巴增生，尤其是毛細胞白血病中十分有效。它可和某些抗腫瘤藥發(fā)揮協(xié)同作用，具有免疫抑制活性。
S9522	Valrubicin	Valrubicin(AD-32) 是一種化療藥物，用于治療膀胱癌。Valrubicin 可抑制 TPA- 和 PDBu- 誘導的 PKC 活化，對應的IC50值分別為0.85 μM 和 1.25 μM。
S4345	Pentoxifylline	Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity.
S4353	Terfenadine	Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
S8848	Futibatinib (TAS-120)	Futibatinib (TAS-120) is an irreversible fibroblast growth factor receptor (FGFR) inhibitor which inhibits all 4 subtypes of FGFR with enzyme IC50 values of 1.8 nM, 1.4 nM, 1.6 nM and 3.7 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
S4357	Tacrine HCl	Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist. Tacrine hydrochloride hydrate is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
S4360	Tolmetin Sodium	Tolmetin(MCN2559) is a non-steroidal anti-inflammatory drug of the arylalkanoic acids.
S4368	Carbenoxolone Sodium	Carbenoxolone, a synthetic derivative of glycyrrhetinic acid, is also used as a blocker of the enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD), of pannexon membrane channels (comprising 6 subunits of pannexin) and the related innexon channels.
S4377	Imipramine HCl	Imipramine (Melipramine,G 22355) is a tricyclic antidepressant (TCA) of the dibenzazepine group, mainly used in the treatment of major depression and enuresis (inability to control urination).
S4382	Pyrilamine Maleate	Pyrilamine Maleate (Mepyramine) is a histamine H1 receptor inverse agonist, it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling.
S8206	Ivosidenib (AG-120)	Ivosidenib (AG-120) 是一種具有口服活性的IDH1（isocitrate dehydrogenase type 1）抑制劑，具有潛在的抗腫瘤活性。
S2807	Dabrafenib (GSK2118436)	Dabrafenib是一種突變型BRAF^V600E特異性抑制劑，無細胞試驗中IC50為0.7 nM，作用于B-Raf(wt)和c-Raf效果分別低7和9倍。
S6624	Avatrombopag	Avatrombopag (AKR-501,E5501,YM477)是一種可口服的血小板生成素受體（c-Mpl）激動劑，可增加血小板數(shù)量，但不激活血小板。
S4115	Hydroxypropyl Cellulose	Hydroxypropyl Cellulose 是纖維素的衍生物，具有水溶性和有機溶解性，用來作為食品添加劑，作為DNA分離的篩分介質。
S1346	Heparin sodium	Heparin sodium 屬于一類葡聚糖，可以和多種蛋白相互作用產(chǎn)生多種生物活性。Heparin 主要通過與AT III相互作用而被用作抗凝劑，通過增強AT-III介導的抑制凝血因子作用，包括thrombin 和 factor Xa。肝素可防止自噬。
S2305	Grape Seed Extract	Grape Seed Extract 是整個葡萄籽中的工業(yè)衍生物，具有很高濃度的維生素E，類黃酮，亞油酸，和OPCs。
S2609	Inulin	Inulin是淀粉，存在于許多植物的塊莖和根中，因為它可水解為果糖，所以歸類為果聚糖。

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